AWWI - Phuan,P.W.; Zorn,J.A.; Safar,J.; Giles,K.; Prusiner,S.B.; Cohen,F.E.; May,B.C.H. - Discriminating between cellular and misfolded prion protein by using affinity to 9-aminoacridine compounds - Journal of General Virology 2007 Apr; 88(4): 1392-401
APBC - Aguzzi,A.; Barbara,J.A.J.; Brown,P.; Budka,H.; Diringer,H.; Dormont,D.; Flanagan,P.; Heeschen,W.; Hope,J.; Hörnlimann,B.; Kenney,K.; Masters,C.; Macnaughton,M.R.; Pocchiari,M.; Rohwer,R.G.; Safar,J.G.; Somogyi,A.; Tateishi,J.; Taylor,D.M.; van Duijn,C.M.; Wilesmith,J.W.; Will,R.G.; Wisher,M.H.; Asher,D.M.; de Pedro Cuesta,J.; Feek,C.; Hasebe,K.; Horaud,F.; Löwer,J.; Minor,P.D.; Nandapalan,P.; Pavlov,A.; Perez,A.C.; Ricketts,M.N.; Vicari,G.; van Aken,W.G.; Beal,R.; Menache-Aronson,D.; Bradley,R.; Bailey,A.C.; Chalumeau,H.P.; Garland,A.; Brooks,W.; Schrieber,R.; Sprengers,E.; Andjaparidze,A.G.; Bolis,C.L.; Emmanuel,J.C.; Griffiths,E.; Heymann,D.L.; Kaboyo,W.; Meslin,F.X.; Miyagawa,S.; Padilla Marroquin,A.; Schudel,A.; Zeidler,M. - Medicinal and other products and human and animal transmissible spongiform encephalopathies - memorandum from a WHO meeting - Bulletin of the World Health Organization 1997; 75(N6): 505-13
AQXR - Bouzamondo-Bernstein,E.; Hopkins,S.D.; Spilman,P.; Uyehara-Lock,J.H.; Deering,C.; Safar,J.G.; Prusiner,S.B.; Ralston,H.J.3rd; DeArmond,S.J. - The neurodegeneration sequence in prion diseases: evidence from functional, morphological and ultrastructural studies of the GABAergic system. - Journal of Neuropathology and Experimental Neurology 2004 Aug; 63(8): 882-99
ABUU - Brown,P.; Kenney,K.; Little,B.; Ironside,J.; Will,R.; Cervenakova,L.; Bjork,R.J.; San Martin,R.A.; Safar,J.G.; Roos,R.; Haltia,M.; Gibbs,C.J.Jr.; Gajdusek,D.C. - Intracerebral distribution of infectious amyloid protein in spongiform encephalopathy - Annals of Neurology 1995 Aug; 38(2): 245-53
ACLD - Ceroni,M.; Piccardo,P.; Safar,J.G.; Gajdusek,D.C.; Gibbs,C.J.Jr. - Scrapie infectivity and prion protein are distributed in the same pH range in agarose isoelectric focusing - Neurology 1990 Mar; 40(3 Pt 1): 508-13
ADHZ - Di Martino,A.; Safar,J.G.; Gibbs,C.J.Jr. - The consistent use of organic solvents for purification of phospholipids from brain tissue effectively removes scrapie infectivity - Biologicals 1994 Sep; 22(3): 221-5
ADIA - Di Martino,A.; Safar,J.G.; Callegaro,L.; Salem,N.Jr.; Gibbs,C.J.Jr. - Ganglioside composition changes in spongiform encephalopathies: analyses of 263K scrapie-infected hamster brains. - Neurochemical Research 1993 Aug; 18(8): 907-13
ADIC - Di Martino,A.; Safar,J.G.; Ceroni,M.; Gibbs,C.J.Jr. - Inactivation of the scrapie agent in a scaled-down procedure for the purification of gangliosides from brain tissue - Developments in Biological Standardization 1993; 80: 187-94
ADID - Di Martino,A.; Safar,J.G.; Ceroni,M.; Gibbs,C.J.Jr. - Purification of non-infectious ganglioside preparations from scrapie-infected brain tissue - Archives of Virology 1992; 124(1-2): 111-21
AENN - Gibbs,C.J.Jr.; Safar,J.G.; Ceroni,M.; Di Martino,A.; Clark,W.W.; Hourrigan,J.L. - Experimental transmission of scrapie to cattle - Lancet 1990 May 26; 335(8700): 1275
APXS - Goldman,J.S.; Miller,B.L.; Safar,J.G.; de Tourreil,S.; Martindale,J.L.; Prusiner,S.B.; Geschwind,M.D. - When sporadic disease is not sporadic: the potential for genetic etiology. - Archives of Neurology 2004 Feb; 61(2): 213-6
AGED - Kaneko,K.; Ball,H.L.; Wille,H.; Zhang,H.; Groth,D.; Torchia,M.; Tremblay,P.; Safar,J.G.; Prusiner,S.B.; DeArmond,S.J.; Baldwin,M.A.; Cohen,F.E. - A synthetic peptide initiates Gerstmann-Sträussler-Scheinker (GSS) disease in transgenic mice - Journal of Molecular Biology 2000 Jan 28; 295(4): 997-1007
AXEO - King,D.J.; Safar,J.G.; Legname,G.; Prusiner,S.B. - Thioaptamer interactions with prion proteins: sequence-specific and non-specific binding sites. - Journal of Molecular Biology 2007 Jun 15; 369(4): 1001-14
AOVQ - Leclerc,E.; Ball,H.L.; Safar,J.G.; Serban,H.; Prusiner,S.B.; Burton,D.R.; Williamson,A. - Copper induces conformational changes in the N-terminal part of cell-surface PrPc - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - BR-117
ANRL - Leclerc,E.; Peretz,D.; Ball,H.L.; Solforosi,L.; Legname,G.; Safar,J.G.; Serban,A.; Prusiner,S.B.; Burton,D.R.; Williamson,R.A. - Conformation of PrPc on the cell surface as probed by antibodies - Journal of Molecular Biology 2003 Feb 14; 326(2): 475-83
ATDL - Lee,I.S.; Long,J.R.; Prusiner,S.B.; Safar,J.G. - Selective precipitation of prions by polyoxometalate complexes - Journal of the American Chemical Society 2005 Oct 12; 127(40): 13802-3
ATYE - Peretz,D.; Supattapone,S.; Giles,K.; Vergara,J.; Freyman,Y.; Lessard,P.; Safar,J.G.; Glidden,D.V.; McCulloch,C.; Nguyen,H.O.B.; Scott,M.; DeArmond,S.J.; Prusiner,S.B. - Inactivation of prions by acidic sodium dodecyl sulfate - Journal of Virology 2006 Jan; 80(1): 322-31
AJJE - Pergami,P.; Jaffe,H.; Safar,J.G. - Semipreparative chromatographic method to purify the normal cellular isoform of the prion protein in nondenatured form - Analytical Biochemistry 1996 Apr 5; 236(1): 63-73
AJJP - Perrier,V.; Kaneko,K.; Safar,J.G.; Vergara,J.; Tremblay,P.; DeArmond,S.J.; Cohen,F.E.; Prusiner,S.B.; Wallace,A.C. - Dominant-negative inhibition of prion replication in transgenic mice - Proceedings of the National Academy of Sciences of the United States of America 2002 Oct 1; 99(20): 13079-84
AJJQ - Perrier,V.; Wallace,A.C.; Kaneko,K.; Safar,J.G.; Prusiner,S.B.; Cohen,F.E. - Mimicking dominant negative inhibition of prion replication through structure-based drug design - Proceedings of the National Academy of Sciences of the United States of America 2000 May 23; 97(11): 6073-8
AJLG - Piccardo,P.; Safar,J.G.; Ceroni,M.; Gajdusek,D.C.; Gibbs,C.J.Jr. - Immunohistochemical localization of prion protein in spongiform encephalopathies and normal brain tissue - Neurology 1990 Mar; 40(3 Pt 1): 518-22
AXUT - Price,J.C.; Deering,C.; Wille,H.; Safar,J.G.; Prusiner,S.B. - Mechanistic Insights into in Vitro Amplification of Prions - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Protein Misfolding P01.04
AWMX - Safar,J.G.; Wille,H.; Geschwind,M.D.; Deering,C.; Latawiec,D.; Serban,A.; King,D.J.; Legname,G.; Weisgraber,K.H.; Mahley,R.W.; Miller,B.L.; DeArmond,S.J.; Prusiner,S.B. - Prion clearance and plasma lipoproteins - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions PA-47
AUZS - Safar,J.G.; Wille,H.; Geschwind,M.D.; Deering,C.; Latawiec,D.; Serban,A.; King,D.J.; Legname,G.; Weisgraber,K.H.; Mahley,R.W.; Miller,B.L.; DeArmond,S.J.; Prusiner,S.B. - Human prions and plasma lipoproteins - Proceedings of the National Academy of Sciences of the United States of America 2006 Jul 25; 103(30): 11312-7
ATDZ - Safar,J.G.; DeArmond,S.J.; Kociuba,K.; Deering,C.; Didorenko,S.; Bouzamondo-Bernstein,E.; Prusiner,S.B.; Tremblay,P. - Prion clearance in bigenic mice - Journal of General Virology 2005 Oct; 86(10): 2913-23
ASXU - Safar,J.G.; Kellings,K.; Serban,A.; Groth,D.; Cleaver,J.E.; Prusiner,S.B.; Riesner,D. - Search for a prion-specific nucleic acid - Journal of Virology 2005 Aug; 79(16): 10796-806
ARSR - Safar,J.G.; Geschwind,M.D.; Deering,C.; Didorenko,S.; Sattavat,M.; Sanchez,H.; Serban,A.; Vey,M.; Baron,H.; Giles,K.; Miller,B.L.; DeArmond,S.J.; Prusiner,S.B. - Diagnosis of human prion disease - Proceedings of the National Academy of Sciences of the United States of America 2005 Mar 1; 102(9): 3501-6
AOYO - Safar,J.G. - Protease-sensitive conformers of disease-causing prion protein (PrPsc): Detection and role in pathogenesis - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Oral sessions OS-32
ACDH - Safar,J.G.; Scott,M.R.D.; Monaghan,J.; Deering,C.; Didorenko,S.; Vergara,J.; Ball,H.L.; Legname,G.; Leclerc,E.; Solforosi,L.; Serban,H.; Groth,D.; Burton,D.R.; Prusiner,S.B.; Williamson,R.A. - Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice - Nature Biotechnology 2002 Nov 1; 20(11): 1147-50
AKHK - Safar,J.G.; Cohen,F.E.; Prusiner,S.B. - Quantitative traits of prion strains are enciphered in the conformation of the prion protein - Archives of Virology. Supplementum 2000(16): 227-35
AAQE - Safar,J.G.; Prusiner,S.B.; DeArmond,S.J. - Diagnose und Pathogenese der Prionerkrankungen - Die gelben Hefte - Immunbiologische Informationen 3/1999; 39: 79-90
AKHL - Safar,J.G.; Wille,H.; Itri,V.; Groth,D.; Serban,H.; Torchia,M.; Cohen,F.E.; Prusiner,S.B. - Eight prion strains have PrPsc molecules with different conformations - Nature Medicine 1998 Oct; 4(10): 1157-65
AKHM - Safar,J.G.; Prusiner,S.B. - Molecular studies of prion diseases - Progress in Brain Research 1998; 117: 421-34
ARVN - Safar,J.G. - Spectroscopic conformational studies of prion protein isoforms and the mechanism of transformation - Seminars in Virology 1996; 7(N3): 207-14
AKHN - Safar,J.G. - The folding intermediate concept of prion protein formation and conformational links to infectivity - Current Topics in Microbiology and Immunology 1996; 207: 69-76
ASIF - Safar,J.G.; Roller,P.P.; Ruben,G.C.; Gajdusek,D.C.; Gibbs,C.J.Jr. - Conformational pathways of scrapie amyloid (prion) protein and the structure-function relationship with infectivity - Research Advances in Alzheimer'S Disease and Related Disorders (Ed. Iqbal, K.; Mortimer, J.A.; Winblad, B.; Wisniewski, H.M.) 1995: 775-81
AKHO - Safar,J.G.; Roller,P.P.; Gajdusek,D.C.; Gibbs,C.J.Jr. - Scrapie amyloid (prion) protein has the conformational characteristics of an aggregated molten globule folding intermediate - Biochemistry 1994 Jul 12; 33(27): 8375-83
AKHP - Safar,J.G. - Infectious amyloid, prions, unconventional viruses, and disease - Neurobiology of Aging 1994 Mar-Apr; 15(2): 279-81
AKHQ - Safar,J.G.; Roller,P.P.; Gajdusek,D.C.; Gibbs,C.J.Jr. - Thermal stability and conformational transitions of scrapie amyloid (prion) protein correlate with infectivity - Protein Science 1993 Dec; 2(12): 2206-16
AKHR - Safar,J.G.; Roller,P.P.; Gajdusek,D.C.; Gibbs,C.J.Jr. - Conformational transitions, dissociation, and unfolding of scrapie amyloid (prion) protein - The Journal of Biological Chemistry 1993 Sep 25; 268(27): 20276-84
AKHS - Safar,J.G.; Ceroni,M.; Gajdusek,D.C.; Gibbs,C.J.Jr. - Differences in the membrane interaction of scrapie amyloid precursor proteins in normal and scrapie- or Creutzfeldt-Jakob disease-infected brains - Journal of Infectious Diseases 1991 Mar; 163(3): 488-94
AKHT - Safar,J.G.; Wang,W.; Padgett,M.P.; Ceroni,M.; Piccardo,P.; Zopf,D.; Gajdusek,D.C.; Gibbs,C.J.Jr. - Molecular mass, biochemical composition, and physicochemical behavior of the infectious form of the scrapie precursor protein monomer - Proceedings of the National Academy of Sciences of the United States of America 1990 Aug; 87(16): 6373-7
AKHU - Safar,J.G. - Scrapie isoform of scrapie-associated protein - Journal of the American Veterinary Medical Association 1990 May 15; 196(10): 1681
AKHV - Safar,J.G.; Ceroni,M.; Piccardo,P.; Gajdusek,D.C.; Gibbs,C.J.Jr. - Scrapie-associated precursor proteins: antigenic relationship between species and immunocytochemical localization in normal, scrapie, and Creutzfeldt-Jakob disease brains. - Neurology 1990 Mar; 40(3 Pt 1): 513-7
AKHW - Safar,J.G.; Ceroni,M.; Piccardo,P.; Liberski,P.P.; Miyazaki,M.; Gajdusek,D.C.; Gibbs,C.J.Jr. - Subcellular distribution and physicochemical properties of scrapie-associated precursor protein and relationship with scrapie agent - Neurology 1990 Mar; 40(3 Pt 1): 503-8
AKQH - Scott,M.R.D.; Safar,J.G.; Telling,G.; Nguyen,O.; Groth,D.; Torchia,M.; Koehler,R.; Tremblay,P.; Walther,D.; Cohen,F.E.; DeArmond,S.J.; Prusiner,S.B. - Identification of a prion protein epitope modulating transmission of bovine spongiform encephalopathy prions to transgenic mice - Proceedings of the National Academy of Sciences of the United States of America 1997 Dec 23; 94(26): 14279-84
ALES - Stöckel,J.; Safar,J.G.; Wallace,A.C.; Cohen,F.E.; Prusiner,S.B. - Prion protein selectively binds copper(II) ions - Biochemistry 1998 May 19; 37(20): 7185-93
ALGS - Supattapone,S.; Wille,H.; Uyechi,L.; Safar,J.G.; Tremblay,P.; Szoka,F.C.Jr.; Cohen,F.E.; Prusiner,S.B.; Scott,M.R.D. - Branched polyamines cure prion-infected neuroblastoma cells - Journal of Virology 2001 Apr; 75(7): 3453-61
ALGW - Supattapone,S.; Bosque,P.J.; Muramoto,T.; Wille,H.; Aagaard,C.; Peretz,D.; Nguyen,H.O.B.; Heinrich,C.; Torchia,M.; Safar,J.G.; Cohen,F.E.; DeArmond,S.J.; Prusiner,S.B.; Scott,M.R.D. - Prion protein of 106 residues creates an artifical transmission barrier for prion replication in transgenic mice - Cell 1999 Mar 19; 96(6): 869-78
AWOP - Tamgüney,G.; Giles,K.; Bosque,P.J.; Miller,M.W.; Safar,J.G.; DeArmond,S.J.; Prusiner,S.B. - Transmission of CWD to transgenic mice - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions PR-32
AVGQ - Tamgüney,G.; Giles,K.; Bouzamondo-Bernstein,E.; Bosque,P.J.; Miller,M.W.; Safar,J.G.; DeArmond,S.J.; Prusiner,S.B. - Transmission of elk and deer prions to transgenic mice - Journal of Virology 2006 Sep; 80(18): 9104-14
APWB - Tremblay,P.; Ball,H.L.; Kaneko,K.; Groth,D.; Hegde,R.S.; Cohen,F.E.; DeArmond,S.J.; Prusiner,S.B.; Safar,J.G. - Mutant PrPsc conformers induced by a synthetic peptide and several prion strains - Journal of Virology 2004 Feb; 78(4): 2088-99
AMFK - Wang,W.T.; Safar,J.G.; Zopf,D. - Analysis of inositol by high-performance liquid chromatography - Analytical Biochemistry 1990 Aug 1; 188(2): 432-5
AWQM - Wille,H.; Latawiec,D.; Serban,A.; Murugesu,M.; Deering,C.; Prusiner,S.B.; Long,J.R.; Safar,J.G. - Growing 2D prion crystals from polyoxometalate complexes - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions S-30