NR AANC
AU anonym
TI New variant of Creutzfeldt-Jakob disease (V-CJD) - France
QU Canada Communicable Disease Report 1996 May 15; 22(10): 79-80
IA http://www.phac-aspc.gc.ca/publicat/ccdr-rmtc/96vol22/dr2210ed.html
PT case reports; journal article
VT
The reported occurrence in the United Kingdom of a new variant of Creutzfeldt-Jakob disease (V-CJD) has led to the re-examination of cases identified in France in latter years. In 1992-1994, in addition to cases observed in patients formerly treated by growth hormone extracts, 135 cases were identified (about 0.8 cases per million population per year). Of the five cases concerning younger subjects, two were genetically determined and one was subsequent to a human dura mater graft; no iatrogenic or genetic risk factor could be identified in two cases:
- a 37-year-old male, for whom no specific investigation results are available;
- a 26-year-old male, who died recently in Lyons and in whom histopathologic observations are similar to those reported from the United Kingdom. The case is still under investigation and no new conclusions can be drawn at present.
The protective mechanisms set up in France since 1990 are regularly assessed and relevant WHO recommendations are rigorously applied. CJD has been included among the compulsory notifiable diseases; the creation of an expert committee at the Ministry of Health and the clinical and neuropathologic reassessment of cases observed in recent years will assist in identifying new or hitherto unsuspected elements concerning this rare disease.
Source: WHO Weekly Epidemiological Record, Vol 71, No 16, 1996.
MH Adult; Creutzfeldt-Jakob Syndrome/*epidemiology/pathology; France/epidemiology; Humans; Incidence; Male
SP englisch
PO Kanada