NR AAVV
AU Awerbuch,G.; Peterson,P.; Sandyk,R.
TI Elevated cerebrospinal fluid lactic acid levels in Creutzfeldt-Jakob disease
QU International Journal of Neuroscience 1988 Sep; 42(1-2): 1-5
PT journal article
AB The concentration of cerebrospinal fluid (CSF) lactic acid was determined in three patients with biopsy proven Creutzfeldt-Jakob disease (CJD). When compared with twenty demented patients diagnosed as having either Alzheimer's disease or multi-infarct dementia, the CSF lactic acid values of the CJD patients were significantly elevated (p less than .001). Elevated CSF lactic acid levels may be an important biochemical marker of CJD and useful in the differential diagnosis of dementia.
IN Bei 3 Creutzfeldt-Jakob-Patienten wurden in der Rückenmarksflüssigkeit deutlich höhere Milchsäurekonzentrationen als bei 20 Patienten mit Alzheimer oder Multiinfarktdemenzen festgestellt.
MH Aged; Aged, 80 and over; Alzheimer Disease/cerebrospinal fluid; Comparative Study; Creutzfeldt-Jakob Syndrome/*cerebrospinal fluid/pathology; Dementia, Multi-Infarct/cerebrospinal fluid; Female; Human; Lactates/*cerebrospinal fluid; Lactic Acid; Male; Middle Age
AD Department of Neurology, Arizona Health Sciences Center, Tucson 85724.
SP englisch
PO England