NR AAWN
AU Bahmanyar,S.; Liem,R.K.; Griffin,J.W.; Gajdusek,D.C.
TI Characterization of antineurofilament autoantibodies in Creutzfeldt-Jakob disease
QU Journal of Neuropathology and Experimental Neurology 1984 Jul; 43(4): 369-75
PT journal article
AB The antineurofilament antibodies found in the serum of a chimpanzee with experimental Creutzfeldt-Jakob disease reacted specifically with the 200,000-dalton polypeptide of the purified neurofilament triplet. They also reacted strongly with thoroughly characterized neurofilament swellings of proximal axons of spinal cord motoneurons from beta,beta' iminodipropionitrile (IDPN)-intoxicated rats.
MH Animal; Autoantibodies/*analysis; Creutzfeldt-Jakob Syndrome/*immunology/pathology; Cytoskeleton/*immunology/pathology; Human; Rats; Rats, Inbred Strains; Spinal Cord/pathology; Support, U.S. Gov't, P.H.S.
SP englisch
PO USA