NR ABBL
AU Bastian,F.O.; Jennings,R.A.; Gardner,W.A.
TI Antiserum to scrapie-associated fibril protein cross-reacts with Spiroplasma mirum fibril proteins
QU Journal of Clinical Microbiology 1987 Dec; 25(12): 2430-1
IA http://www.pubmedcentral.gov/articlerender.fcgi?tool=pubmed&pubmedid=2892856
PT journal article
AB Protease-resistant fibril proteins purified from Spiroplasma mirum and from Creutzfeldt-Jakob disease-infected brain tissues reacted with antisera to scrapie-associated fibrils on Western immunoblot analysis. These data suggest that there are conformational similarities among spiroplasma proteins and infection-specific proteins of the transmissible spongiform encephalopathies.
IN Proteaseresistente Proteinfibrillen aus Spiroplasma mirum sollen im Western blot mit dem selben Antiserum reagiert haben, wie Hirngewebe aus einem Creutzfeldt-Jakob-Patienten.
MH Animals; Bacterial Proteins/*immunology; Creutzfeldt-Jakob Syndrome/*immunology; Cross Reactions; Humans; Immunoassay; Nerve Tissue Proteins/*immunology; PrP 27-30 Protein; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Spiroplasma/*immunology
AD Department of Pathology, College of Medicine, University of South Alabama, Mobile 36617.
SP englisch
PO USA