NR ABHO

AU Bert,J.; Vuillon-Cacciuttolo,G.; Balzamo,E.; de Micco,P.; Gambarelli,D.; Tamalet,J.; Gastaut,H.

TI Appearance of EEG changes reminiscent of a secondary generalized epilepsy in a rhesus monkey inoculated with a strain of kuru

QU Epilepsia 1978 Jun; 19(3): 257-64

PT journal article

AB In a group of rhesus monkeys (Macaca mulatta) inoculated intracerebrally and intravenously with a strain (Enage strain rhesus L6 56) of kuru already passaged in rhesus monkeys, 1 monkey presented the typical EEG pattern of epileptogenic encephalopathy reminiscent of the Lennox-Gastaut syndrome. This observation provides no direct evidence for the viral origin of epilepsies of this type. It does, however, show that it is possible to induce an epileptogenic encephalopathy by an unconventional infectious agent.

IN Mit einem bereits an Rhesusaffen adaptierten Kuru-Agens (L6 56) wurden Rhesusaffen intrazerebral inokuliert. Einer der Affen entwickelte die typischen EEG-Muster einer epileptichen Encephalopathie wie beim Lennox-Dämmerzustand.

MH Animal; *Electroencephalography; Epilepsy/etiology/*physiopathology; Haplorhini; Kuru/*physiopathology; Macaca mulatta

SP englisch

PO USA

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