NR ACLL
AU Cervos-Navarro,J.; Cruz-Sanchez,F.; Gimeno-Alava,A.; Ferszt,R.
TI Intranuclear vacuoles in Creutzfeldt-Jakob disease
QU Neuropathology and Applied Neurobiology 1986 Sep-Oct; 12(5): 477-82
PT journal article
AB In an electron microscopic study of brain biopsy material from a case with Creutzfeldt-Jakob disease intranuclear vacuoles containing membrano-vesicular structures were found. To our knowledge this finding has not been previously reported in human spongiform encephalopathies. It may represent a specific alteration associated with Creutzfeldt-Jakob disease, and suggests the possibility of nuclear infection.
MH Biopsy; Case Report; Cell Nucleus/ultrastructure; Creutzfeldt-Jakob Syndrome/*pathology; Frontal Lobe/*ultrastructure; Human; Inclusion Bodies/ultrastructure; Male; Microscopy, Electron; Middle Age; Support, Non-U.S. Gov't; Vacuoles/ultrastructure
SP englisch
PO England