NR ADCD
AU de Micco,P.
TI [Cellular fusion induced in vitro by the mouse scrapie agent]
OT Fusion cellulaire induite in vitro par l'agent du scrapie de la Souris
QU Comptes Rendus des Seances de l'Academie des Sciences. Serie D, Sciences Naturelles 1979 Apr 23; 288(15): 1211-4
PT journal article
AB A method is described to demonstrate and measure the cell-fusion in vitro induced by viruses. This technique has been established using Sendai virus. It has been used to study the fusing ability of the Scrapie agent which is responsible of a slowly progressing spongiform encephalopathy in Mice. In Vero cells, the Scrapie agent induces a fusion which appears slowly and remains moderate. This test can help to detect the human spongiform encephalopathies.
MH Animal; Cell Fusion; Cells, Cultured; Encephalitis, Arbovirus/diagnosis/pathology; English Abstract; In Vitro; Mice; Prions/*physiology
SP französisch
PO Frankreich