NR ADCJ
AU de Reuck,J.; de Coster,W.; vander Eecken,H.; Daneels,P.
TI Creutzfeldt-Jakob disease: a comparative light-microscopic, histochemical and electron-microscopic study.
QU European Neurology 1975; 13(2): 154-66
PT journal article
AB The morphological and histochemical findings in a brain biopsy of a case of Creutzfeldt-Jakob disease are compared. The histochemical changes in the cytoplasm of the neurons precede the morphological alterations found with the electron microscope. In this way the neuronal enzymatic failure can explain the clinical picture of this disease.
MH Adenosinetriphosphatase/metabolism; Aged; Astrocytes/enzymology/ultrastructure; Autopsy; Biopsy; Brain/*ultrastructure; Comparative Study; Creutzfeldt-Jakob Syndrome/metabolism/*pathology; Cytoplasm/ultrastructure; Female; Human; Lipoamide Dehydrogenase/metabolism; Lipofuscin/metabolism; Lysosomes/ultrastructure; Mitochondria/ultrastructure; Neurons/enzymology/ultrastructure; Nucleotidases/metabolism; Oxidoreductases/metabolism
SP englisch
PO Schweiz