NR ADPH

AU Draganescu,N.

TI [Presenile dementia (Creutzfeldt-Jakob disease). Clinical and experimental data on a newly reported case]

OT La demence presenile (maladie de Creutzfeldt-Jakob). Donnees cliniques et experimentales sur un nouveau cas enregistre.

QU Virologie 1988 Oct-Dec; 39(4): 257-60

PT journal article

AB A newly recorded case of presenile dementia (Creutzfeldt-Jakob disease) is discussed. The disease is experimentally transmissible to guinea pigs, after a long incubation period. From a pathomorphological point of view the experimental disease in the guinea pig is characterized by spongiosis, proliferative glial reaction, disappearance of neurons and of Purkinje's cells.

MH Animal; Brain/pathology; Case Report; Comparative Study; Creutzfeldt-Jakob Syndrome/diagnosis/*pathology/transmission; Electroencephalography; English Abstract; Female; Guinea Pigs; Human; Middle Age

AD Institut de Virologie Stefan S. Nicolau, Bucarest, Roumanie.

SP französisch

PO Rumänien

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