NR ADSG
AU Edskes,H.K.
TI Protein-based inheritance in Saccharomyces cerevisiae: [URE3] as a prion form of the nitrogen regulatory protein Ure2.
QU Research in Microbiology 2001 Sep; 152(7): 605-12
PT journal article; review; review, tutorial
AB The [URE3] element of the yeast Saccharomyces cerevisiae results from the presence of an altered form of the nitrogen regulatory protein Ure2. This altered form acts as an infectious protein (prion). Genes affecting [URE3] initiation and propagation should give valuable information about prion diseases as well as other conformational diseases.
ZR 51
MH *Gene Expression Regulation, Fungal; Nitrogen/*metabolism; Prions/chemistry/*genetics/metabolism; Saccharomyces cerevisiae/*genetics/metabolism; Saccharomyces cerevisiae Proteins/chemistry/*genetics/metabolism
AD Laboratory of Biochemistry and Genetics, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892-0830, USA. edskes@helix.nih.gov
SP englisch
PO Frankreich