NR ADWZ
AU Federico,A.; Annunziata,P.; Malentacchi,G.
TI Neurochemical changes in Creutzfeldt-Jakob disease
QU Journal of Neurology. Zeitschrift für Neurologie 1980; 223(2): 135-46
PT journal article
AB A biochemical study of a case affected by Creutzfeldt-Jakob disease is reported. Changes were found in soluble and insoluble proteins, glycoproteins and mucopolysaccharides and in total lipids, glycolipids, phospholipids and gangliosides. Also CNPase, choline acetyltransferase, 5'-nucleotidase and several glycosidases have an altered activity. All these data give a complete neurochemical pattern of the changes underlying the morphological and functional alterations in this disease.
MH Aged; Body Water/metabolism; Brain/enzymology; Creutzfeldt-Jakob Syndrome/*enzymology; Female; Gangliosides/metabolism; Glycoproteins/metabolism; Glycosaminoglycans/metabolism; Glycoside Hydrolases/metabolism; Human; Lipids/metabolism; Nerve Tissue Proteins/metabolism
SP englisch
PO Westdeutschland