NR ADZA
AU Field,E.J.; Shenton,V.K.; Jenssen,H.L.; Keohler,H.; Gunther,J.K.
TI [Method of electrophoretic mobility of macrophages and its use in clinical immunology]
OT Metod elektroforeticheskoi podvizhnosti makrofagov i ego primenenie v klinicheskoi immunologii
QU Zhurnal Mikrobiologii, Epidemiologii i Immunobiologii 1978 Mar(3): 70-5
PT journal article
AB A test of measurement of the electrophoretic mobility of macrophages (EMM) is used for detection of the product secreted by the sensitized lymphocytes after the contact with the antigen. Thus, by reduction of the macrophage mobility it is possible to assess the sensitization level of the lymphocyte population under study. This offers a possibility of using this test for the diagnosis of some infectious diseases, for provisional diagnosis of malignant growth, and also of destructive affections of the nervous system. The EMM test finds wide application in the determination of compatibility of donor's and the recipient's tissues before the transplantation, and also to assess the efficacy of immunodepressive therapy.
MH Animal; Antilymphocyte Serum/pharmacology; Electrophoresis/*methods; English Abstract; Histocompatibility Testing; Human; Leukoplakia, Oral/diagnosis; Lymphocytes/immunology; Macrophage Migration-Inhibitory Factors/*secretion; Macrophages/*immunology/secretion; Mice; Multiple Sclerosis/diagnosis; Neoplasms/diagnosis; Scrapie/diagnosis; Sheep; Sheep Diseases/diagnosis
SP russisch
PO Sowjetunion