NR AECO

AU Forster,M.; Heath,A.; Afzal,M.

TI Application of distance geometry to 3D visualization of sequence relationships

QU Bioinformatics 1999 Jan; 15(1): 89-90

PT journal article

AB SUMMARY: We describe the application of distance geometry methods to the three-dimensional visualization of sequence relationships, with examples for mumps virus SH gene cDNA and prion protein sequences. Sequence-sequence distance measures may be obtained from either a multiple sequence alignment or from sets of pairwise alignments. AVAILABILITY: C/Perl code and HTML/VRML files from http://www.nibsc.ac.uk/dg3dseq/

MH Algorithms; Animal; *Computer Simulation; DNA, Complementary/chemistry; DNA, Viral/chemistry; Internet; Mathematical Computing; *Models, Molecular; Molecular Conformation; Mumps virus/genetics; Prions/chemistry; RNA/chemistry; Rabbits; Rats; *Sequence Alignment

AD National Institute for Biological Standards and Control, Blanche Lane, South Mimms, Herts. EN6 3QG, UK. mforster@nibsc.ac.uk

SP englisch

PO England

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