NR AEJX
AU Gambarelli,D.; Vuillon-Cacciuttolo,G.; Toga,M.; Bert,J.
TI Anatomical study of experimental kuru in the Rhesus monkey
QU Acta Neuropathologica 1981; 53(4): 337-41
PT journal article
AB The authors report the morphology and topography of CNS lesions in experimental kuru (third passage) in the rhesus monkey. The main lesions encountered are spongiosis of the neuropile with neuronal vacuolization, moderate astrocytic gliosis, and slight neuronal depopulation. In all cases, lesions predominated in the grey matter of the cerebral hemispheres (cortex, neostriatum). Lesions were minimal in cerebellum and brain stem. The authors compare their results with these observed species of Primates (chimpanzee, spider monkey, marmoset, squirrel monkey).
MH Animal; Brain/pathology; Brain Stem/pathology; Cerebellum/pathology; Cerebral Cortex/pathology; Gliosis/pathology; Kuru/*pathology; Macaca mulatta; Neurons/pathology
SP englisch
PO Westdeutschland