NR AEML

AU Gertz,H.J.; Stoltenburg,G.; Cruz-Sanchez,F.; Lafuente,J.; Schopol,R.

TI [Panencephalopathy of the Creutzfeldt-Jakob disease type]

OT Der panenzephalopathische Typ der Creutzfeldt-Jakob-Krankheit

QU Der Nervenarzt 1988 Feb; 59(2): 110-2

PT journal article

AB Creutzfeldt-Jakob disease (CJD) occurring in later life has a duration of about one year. Gait disturbance, myoclonic jerks, dementia and akinetic mutism occur. Post-mortem examination of the brain shows nerve cell loss, gliosis and spongiform changes of the grey matter. Clinical and neuropathological features of a case of the panencephalopathic type of CJD, with additional extensive degeneration of the cerebral white matter, are described. The panencephalopathic type of CJD is characterized clinically by a longer duration and a biphasic course.

MH Adult; Atrophy; Brain/*pathology; Case Report; Cerebral Cortex/pathology; Creutzfeldt-Jakob Syndrome/*pathology; English Abstract; Female; Human; Myelin Sheath/ultrastructure; Neuroglia/pathology; Neurons/pathology; Spinal Cord/pathology; Tomography, X-Ray Computed

AD Institut für Neuropathologie, Klinikum Steglitz der Freien Universität Berlin.

SP deutsch

PO Westdeutschland

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