NR AEQQ
AU Gold,M.; Rojiani,A.; Murtaugh,R.
TI A 66-year-old woman with a rapidly progressing dementia and basal ganglia involvement
QU Journal of Neuroimaging 1997 Jul; 7(3): 171-5
PT clinical conference; journal article
AB A 66-year-old woman presented with a rapidly progressive dementia initially characterized by an auditory agnosia. She experienced a rapid progression of her aphasia and developed ataxia and myoclonus. An initial neurological evaluation suggested a left parieto-temporal lesion, however, neuroimaging did not reveal any. An MRI of her brain demonstrated highly focal T2 hyperintensities in her basal ganglia. The patient was diagnosed with Creutzfeldt-Jakob Disease (CJD) on the basis of the presence of two proteins in the CSF that are highly sensitive and specific for CJD. Pathological examination confirmed the diagnosis. The differential diagnosis and utility of MRI in patients with CJD is discussed.
MH Aged; Basal Ganglia/pathology; Basal Ganglia Diseases/*diagnosis; Brain/*pathology; Case Report; Creutzfeldt-Jakob Syndrome/complications/*diagnosis; Dementia/etiology; Diagnosis, Differential; Female; Human; *Magnetic Resonance Imaging
AD Department of Neurology, University of South Florida College of Medicine, Tampa 33612, USA
SP englisch
PO USA