NR AEXA
AU Grobet,L.
TI [Genome diagnosis in domestic animals]
OT Diagnostics genomiques chez les animaux domestiques
QU Bulletin et Memoires de l'Academie Royale de Medecine de Belgique 1993; 148(10): 345-56
PT journal article
AB Different contributions to the development and applications of genomic diagnosis methods in domestic animals are reported. DNA fingerprints were used to solve parentage disputes in different species, and to reveal leucochimerism in bovine dizygotic twins. In cattle, an embryo sexing method and a freemartinism diagnosis assay were also developed. The search for molecular markers of the MH (muscular hypertrophy) and R (rouan) bovine genes is described. Prion protein gene polymorphisms are investigated in the framework of a research on the genetics of bovine spongiform encephalopathies. The mutation responsible for the autosomal recessive lethal condition BLAD (bovine leucocyte adhesion deficiency) in Holstein cattle is found in our country, and the carries can be detected by a molecular method. The mutation responsible for the halothane sensitivity in pig can also be detected, what is done to control efficiently the introgression of the stress resistance allele in a Pietrain strain.
MH Animal; Cattle/*genetics; Cattle Diseases/*genetics; Embryo; Encephalopathy, Bovine Spongiform/genetics; English Abstract; Freemartinism/genetics; Genomic Imprinting; Polymorphism (Genetics); Prion Diseases/genetics/veterinary; Sex Determination (Analysis); Swine; Swine Diseases/genetics
AD Service de Genetique factorielle et moleculaire, faculte de Medecine veterinaire, Universite de Liege.
SP französisch
PO Belgien