NR AEZQ
AU Hadlow,W.J.; Prusiner,S.B.; Kennedy,R.C.; Race,R.E.
TI Brain tissue from persons dying of Creutzfeldt-Jakob disease causes scrapie-like encephalopathy in goats
QU Annals of Neurology 1980 Dec; 8(6): 628-32
PT journal article
AB Two goats became affected with an encephalopathy indistinguishable from scrapie 43 months after they were inoculated intracerebrally with 10% suspensions of brain from two persons dying of Creutzfeldt-Jakob disease. Although this observation does not establish the common identity of Creutzfeldt-Jakob disease virus and scrapie virus, it is thought to provide strong evidence of a close etiological relationship between the two diseases.
MH Aged; Animal; Brain/microbiology/*pathology; Brain Diseases/pathology/transmission/*veterinary; Creutzfeldt-Jakob Syndrome/etiology/pathology/*transmission; Female; *Goats; Human; Male; Middle Age; Scrapie/*etiology; Sheep; Support, U.S. Gov't, P.H.S.
SP englisch
PO USA