NR AFIL
AU Hernandez-Palazon,J.; Martinez-Lage,J.F.; Tortosa,J.A.; Garcia-Cayuela,J.M.
TI Anaesthetic management in patients suspected of, or at risk of, having Creutzfeldt-Jakob disease
QU British Journal of Anaesthesia 1998 Apr; 80(4): 516-8
PT journal article
AB We report two young patients who had repeated neurosurgical procedures and who were thought to be at risk of developing Creutzfeldt-Jakob disease (CJD). The first patient had been given a lyophilized dural graft in the course of removal of a cerebellar medulloblastoma 15 yr previously. The second patient had received pituitary-derived growth hormone for treatment of growth hormone deficiency, secondary to a third ventricle teratoma, exised 13 yr earlier. The presence of cerebellar symptoms together with being recipients of growth hormone or dural graft of cadaveric extraction arose suspicion of a diagnosis of CJD in both individuals. Precautions in the anaesthetic and surgical management of these two patients are discussed, and pertinent literature is reviewed briefly.
MH Adolescent; Anesthesia, General/*methods; Case Report; Creutzfeldt-Jakob Syndrome/*transmission; Disease Transmission, Patient-to-Professional/*prevention & control; Drug Contamination; Dura Mater/transplantation; Growth Hormone/adverse effects; Human; Male; *Neurosurgical Procedures; Sterilization
AD Department of Anaesthesia, Virgen de la Arrixaca University Hospital, Murcia, Spain.
SP englisch
PO England