NR AFLM
AU Hoinville,L.J.
TI A review of the epidemiology of scrapie in sheep
QU Revue Scientifique et Technique de l'Office International des Epizooties 1996 Sep; 15(3): 827-52
PT journal article; review; review, tutorial
AB The aim of this review is to summarise and evaluate the data available about the aetiology of scrapie in naturally affected sheep flocks, particularly data concerning the possible transmission of infection between related animals. The author examines data taken from various relevant studies carried out over the last thirty years. The main conclusions are that scrapie is an infectious disease with a genetic influence on the incubation period. The increased risk of disease in the offspring of affected animals is thought to be largely the result of increased genetic susceptibility, with a large proportion of the cases occurring in high-incidence flocks being the result of horizontal transmission of infection.
IN Aufgrund einer Überprüfung entsprechender Studien der letzten 3 Jahrzehnte kommt der Autor in diesem Review zu dem Schluss, dass Scrapie beim Schaf eine Infektionskrankheit sei, die hauptsächlich horizontal übertragen werde und bei der die Nachkommen infizierter Eltern hauptsächlich aufgrund ererbter Empfänglichkeit ein erhöhtes Infektionsrisiko zeigten.
ZR 97
MH Animal; Disease Transmission, Horizontal/veterinary; Disease Transmission, Vertical; Genetic Markers; Genetic Predisposition to Disease; Goat Diseases/epidemiology/genetics/transmission; Goats; Incidence; Risk Factors; Scrapie/*epidemiology/genetics/transmission; Sheep
AD Epidemiology Department, Central Veterinary Laboratory, Addlestone, Surrey, United Kingdom.
SP englisch
PO Frankreich