NR AFPC
AU Hoshi,K.; Yoshino,H.; Urata,J.; Nakamura,Y.; Yanagawa,H.; Sato,T.
TI Creutzfeldt-Jakob disease associated with cadaveric dura mater grafts in Japan
QU Neurology 2000 Sep 12; 55(5): 718-21
PT journal article
AB A nationwide survey and recent information documented 57 patients with Creutzfeldt-Jakob disease (CJD) who had received dura mater grafts during the period between January 1979 and September 1999. At least 54 of these 57 patients received the same brand of dura mater graft from the same processor. Mean age at disease onset in the 57 patients with dural grafts was younger (51.9 years) than that in patients with sporadic CJD (63 years) (p < 0. 0001). Initial symptoms were cerebellar ataxia, disorientation, and visual or oculomotor disturbance.
MH *Cadaver; Creutzfeldt-Jakob Syndrome/*epidemiology/*transmission; Disease Outbreaks; Dura Mater/*transplantation; Human; Japan/epidemiology; Middle Age; Questionnaires; Support, Non-U.S. Gov't
AD Japanese National CJD Surveillance Group, Kohnodai Hospital, Chiba-ken, Japan.
SP englisch
PO USA