NR AFUH
AU Ingrosso,L.; Ladogana,A.; Pocchiari,M.
TI Congo red prolongs the incubation period in scrapie-infected hamsters
QU Journal of Virology 1995 Jan; 69(1): 506-8
PT journal article
AB In scrapie-infected cells, Congo red inhibits both the replication of the infectious agent and accumulation of the protease-resistant form of PrP (PrPres). In this report, we show that Congo red prolongs the incubation periods of hamsters experimentally infected with two different strains of scrapie.
IN Kongo Rot scheint bei Scrapie-infizierten Hamsterzellen die Vermehrung und die Akkumulation des infektiösen, proteaseresistenten Prionproteins zu inhibieren und die Inkubationszeit infizierter Hamster zu verlängern.
ZR 22
MH Animal; Congo Red/*pharmacology; Hamsters; Mesocricetus; PrPsc Proteins/*drug effects; Scrapie/*virology; Support, Non-U.S. Gov't; Virus Replication/*drug effects
AD Laboratory of Virology, Istituto Superiore di Sanita, Rome, Italy.
SP englisch
PO USA