NR AFUZ
AU Iribarren,P.; Cui,Y.H.; Le,Y.; Wang,J.M.
TI The role of dendritic cells in neurodegenerative diseases
QU Archivum Immunologiae et Therapiae Experimentalis 2002; 50(3): 187-96
PT journal article; review; review, tutorial
AB Dendritic cells (DCs) are the most potent antigen-presenting cells (APCs) involved in the induction of adaptive immune responses. The presence of DCs in the central nervous system (CNS) and the active participation of the immune system in a variety of neurodegenerative diseases have been demonstrated. This review will discuss recent findings pertinent to DCs and other antigen-presenting cells in the CNS in health and disease states.
ZR 92
MH Alzheimer Disease/etiology/immunology; Animal; Antigen-Presenting Cells/physiology; Brain/immunology; Dendritic Cells/*physiology; Encephalomyelitis, Experimental Autoimmune/etiology/immunology; Human; Microglia/immunology; Multiple Sclerosis/etiology/immunology; Neurodegenerative Diseases/etiology/*immunology; Prion Diseases/etiology/immunology; Support, U.S. Gov't, P.H.S.
AD Laboratory of Molecular Immunoregulation, Center for Cancer Research, National Cancer Institute at Frederick, Building 560, Room 31-40, Frederick, MD 21702, USA. iribarrenp@mail.ncifcrf.gov
SP englisch
PO Polen