NR AFXR
AU Jacob,F.; Ries,F.; Dicato,M.
TI Prion diseases in man
QU Biomedicine and Pharmacotherapy 1991; 45(9): 379-82
PT journal article; review; review, tutorial
AB Human spongiform encephalopathies (HSE) are uncommon neurodegenerative diseases of unknown etiology. Whilst numerous observations provide arguments for an infectious disorder mediated by an unconventional agent of the so-called prion-type, the recent discovery of predisposing allelic variants suggests that HSE might be considered as genetically linked diseases.
ZR 34
MH Animal; Cattle; Encephalopathy, Bovine Spongiform/genetics/microbiology/*transmission; Human; Nerve Degeneration; Nervous System Diseases/genetics/microbiology; *Prions
AD Hematology-Oncology Department, Centre Hospitalier de Luxembourg.
SP englisch
PO Frankreich