NR AFZS
AU Jeffrey,M.J.
TI A neuropathological survey of brains submitted under the Bovine Spongiform Encephalopathy Orders in Scotland
QU The Veterinary Record 1992 Oct 10; 131(15): 332-7
PT journal article
AB Bovine spongiform encephalopathy was not confirmed histologically in 225 of 829 bovine brains submitted for diagnosis. Several previously described disorders of the central nervous system were observed in these brains as well as disorders not previously recognised in Britain, including bilateral vacuolation of the substantia nigra, hippocampal sclerosis with brainstem neuronal chromatolysis and necrosis, focal symmetrical encephalomalacia and meningio-angiomatosis. Severe cerebellar dysplasia consistent with pre-natal bovine viral diarrhoea - mucosal disease virus infection or mineralisation of the blood vessels of the basal ganglia were interpreted respectively as congenital changes or changes due to ageing and were considered to be of no clinical significance.
MH Animal; Brain/*pathology; Brain Diseases/epidemiology/pathology/*veterinary; Brain Neoplasms/epidemiology/pathology/veterinary; Brain Stem/pathology; Cattle; Cattle Diseases/*epidemiology/pathology; Cerebellum/pathology; Diagnosis, Differential; Encephalitis/epidemiology/pathology/veterinary; Encephalomalacia/epidemiology/pathology/veterinary; Encephalopathy, Bovine Spongiform/*epidemiology/pathology; Hippocampus/pathology; Medulla Oblongata/pathology; Meningoencephalitis/epidemiology/pathology/veterinary; Necrosis; Scotland/epidemiology; Substantia Nigra/pathology
AD Martin J. Jeffrey (m.jeffrey@vla.maff.gov.uk), VLA Lasswade Veterinary Laboratory, Pentlands Science Park, Bush Loan, Penicuik, Edinburgh EH26 OPZ, Scotland, UK
SP englisch
PO England