NR AGAM

AU Jiang,T.T.; Moses,H.; Gordon,H.; Obah,E.

TI Sporadic Creutzfeldt-Jakob disease presenting as major depression

QU Southern Medical Journal 1999 Aug; 92(8): 807-8

PT journal article

AB We describe a 68-year-old white woman who initially had symptoms of major depression and was admitted to a psychiatric hospital where she had electroconvulsive therapy. With failure of psychiatric treatment and subsequent rapidly progressive dementia, she had left frontal brain biopsy. The biopsy revealed spongiform changes, the hallmark of Creutzfeldt-Jakob disease (CJD). We report a case of sporadic CJD with unusual initial presentation of psychiatric symptoms.

MH Aged; Biological Markers; Brain/pathology; Case Report; Creutzfeldt-Jakob Syndrome/*diagnosis; Depressive Disorder/*diagnosis; Diagnostic Errors; Electroencephalography; Female; Human; Prions/analysis

AD Department of Medicine, Greater Baltimore Medical Center, MD, USA

SP englisch

PO USA

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