NR AGAO
AU Jibiki,I.; Fukushima,T.; Kobayashi,K.; Kurokawa,K.; Yamaguchi,N.; Matsuda,H.; Hisada,K.
TI Utility of 123I-IMP SPECT brain scans for the early detection of site-specific abnormalities in Creutzfeldt-Jakob disease (Heidenhain type): a case study.
QU Neuropsychobiology 1994; 29(3): 117-9
PT journal article
AB Serial changes in brain imaging of regional cerebral blood flow with single photon emission computed tomography (SPECT) using N-isopropyl-(iodine-123) p-iodoamphetamine (123I-IMP) were observed in a patient with probable Heidenhain type of Creutzfeldt-Jakob disease, which was characterized by the initial onset of visual symptoms. Corresponding to the visual signs and periodic synchronous discharges localized in the bilateral parietal and occipital regions on EEG, focal hypoperfusion images in the occipital lobes were detected on the SPECT scan before brain X-ray computed tomography and magnetic resonance imaging showed any abnormalities. These results suggest that SPECT brain imaging is useful in the early detection of site-specific abnormalities in Creutzfeldt-Jakob disease.
MH Aged; Amphetamines/diagnostic use; Brain/physiopathology/*radionuclide imaging; Brain Mapping; Case Report; Cerebral Cortex/physiopathology/radionuclide imaging; Creutzfeldt-Jakob Syndrome/physiopathology/*radionuclide imaging; Electroencephalography; Female; Human; Iodine Radioisotopes/diagnostic use; Neurologic Examination; Neuropsychological Tests; *Tomography, Emission-Computed, Single-Photon
AD Department of Neuropsychiatry, Kanazawa University School of Medicine, Japan.
SP englisch
PO Schweiz