NR AGGQ
AU Kawata,A.; Suga,M.; Oda,M.; Hayashi,H.; Tanabe,H.
TI Creutzfeldt-Jakob disease with congophilic kuru plaques: CT and pathological findings of the cerebral white matter.
QU Journal of Neurology, Neurosurgery and Psychiatry 1992 Sep; 55(9): 849-51
PT journal article
AB In a patient whose Creutzfeldt-Jakob disease with congophilic kuru plaques that was proved at necropsy, the early brain CT showed low-density areas in the cerebral white matter before cortical atrophy and ventricular enlargement became apparent. Subsequently, there occurred diffuse white matter lucency and severe brain atrophy. At necropsy, there was severe white matter destruction which was more prominent than cortical neuronal loss. Serial CT scans were of great value for demonstrating the early and predominant changes in the cerebral white matter.
MH Animal; Atrophy; Brain/*pathology; Case Report; Cerebral Cortex/pathology; Creutzfeldt-Jakob Syndrome/*pathology; Female; Human; Kuru/*pathology; Mice; Middle Age; Necrosis; Nerve Degeneration/physiology; Neurons/pathology; *Tomography, X-Ray Computed
AD Tokyo Metropolitan Neurological Hospital, Japan.
SP englisch
PO England