NR AGHN
AU Kelly,J.W.
TI Mechanisms of amyloidogenesis
QU Nature Structural Biology 2000 Oct; 7(10): 824-6
PT news
AB Limitations of the three putative mechanisms of amyloid fibril assembly for explaining Sup35 prion formation have led to the introduction of a fourth model ? nucleated conformational conversion ? that invokes oligomeric intermediates for initiation and assembly.
MH Amyloid/*biosynthesis/metabolism; Fungal Proteins/biosynthesis; Kinetics; Models, Molecular; Molecular Probes; Prions/*biosynthesis
SP englisch
PO USA