NR AGIC
AU Keohane,C.
TI [Prion diseases in men]
OT Les maladies a prions chez l'homme
QU Archives d'Anatomie et de Cytologie Pathologiques 1994; 42(2): 69-75
PT journal article; review; review, tutorial
AB Since the outbreak of "mad cow disease" and, more recently, the occurrence of cases of iatrogenic Creutzfeldt-Jakob disease in children who received pituitary extracts, there has been increasing public awareness and concern regarding the spongiform encephalopathies. These disorders appear to be caused by an extraordinary agent, unlike any previously described, called a "prion". All are progressive dementing diseases which are not associated with any specific immune or inflammatory response. At present there is no effective treatment.
ZR 54
MH Creutzfeldt-Jakob Syndrome/pathology; English Abstract; Gerstmann Syndrome/pathology; Human; Kuru/pathology; Prion Diseases/*pathology; Prions/genetics/pathogenicity
AD Department of Pathology (Neuropathology), Cork Regional Hospital, Wilton, Eire.
SP französisch
PO Frankreich