NR AGSN
AU Kostka,V.M.; Groschup,M.H.; Kaleta,E.F.; Schroder,J.
TI Failure to induce formation of proteinase K resistant fibrils in pigeons through experimental infection with paramyxovirus type 1
QU Deutsche tierärztliche Wochenschrift 1997 May; 104(5): 174-5
PT journal article
AB Ten racing pigeons were infected experimentally with the paramyxovirus (PMV) type 1 of the pigeon. Within twelve weeks of observation, they were euthanized at different times. Their brains were examined for proteinase K resistant fibrils and histopathologically for spongiform lesions. No proteinase K resistant fibrils and no spongiform lesions could be detected in any case. Therefore, it is estimated that PMV type 1 of the pigeon is not likely to induce pathogenic mechanisms assumed for transmissible spongiform encephalopathies.
MH Animal; Brain/*pathology/virology; Chickens; *Endopeptidase K; *Paramyxoviruses, Avian; Pigeons; Prions/isolation & purification; Rubulavirus Infections/*pathology
AD Institute for Avian Diseases, Justus-Liebig-Universität Giessen, Germany.
SP englisch
PO Deutschland