NR AHCQ
AU Leach,R.H.; Matthews,W.B.; Will,R.
TI Creutzfeldt-Jakob disease. Failure to detect spiroplasmas by cultivation and serological tests.
QU Journal of the Neurological Sciences 1983 Jun; 59(3): 349-53
PT journal article
AB Specimens from confirmed cases of Creutzfeldt-Jakob disease (CJD) were examined for evidence of spiroplasma infection. No spiroplasmas or other mycoplasmas were cultivated from brain tissue of 18 cases and no antibodies to several recognised Spiroplasma spp. were detected in sera from 15 patients. These negative cultural and serological results provide no support for published suggestions that CJD brain contains structures morphologically resembling spiroplasmas.
MH Antibodies/analysis; Brain/microbiology; Cells, Cultured; Creutzfeldt-Jakob Syndrome/*microbiology; Fluorescent Antibody Technique; Human; Middle Age; Mycoplasma/isolation & purification; Serology; Spiroplasma/immunology/*isolation & purification
SP englisch
PO Niederlande