NR AHDO
AU Lee,K.E.; Loh,N.K.; Tan,A.K.; Lee,W.L.; Tjia,H.T.
TI Creutzfeldt-Jakob disease presenting with visual blurring, diplopia and visual loss: Heidenhain's variant.
QU Annals of the Academy of Medicine, Singapore 1998 Nov; 27(6): 854-6
PT journal article
AB Focal electroencephalographic abnormalities as described in Heidenhain's variant of Creutzfeldt-Jakob disease are uncommon. We report a 73-year-old male presenting with visual symptoms, right hemianopia and rapidly progressive dementia. Myoclonus was synchronous with generalised periodic epileptiform discharges on electroencephalography (EEG). In addition, there were periodic focal sharp waves at the left occipital region. Diffusion-weighted magnetic resonance brain images showed slightly increased signal intensity in the occipital parasagittal area, left more than right. 14-3-3 protein was detected in the cerebrospinal fluid. The patient died within 5 months of presentation.
MH Aged; Brain/pathology; Case Report; Creutzfeldt-Jakob Syndrome/complications/*diagnosis; Dementia/complications; Diplopia/etiology; Electroencephalography; Human; Magnetic Resonance Imaging; Male; Vision Disorders/*etiology
AD Department of Neurology, Tan Tock Seng Hospital, Singapore.
SP englisch
PO Singapur