NR AHHN
AU Liberski,P.P.; Barcikowska,M.
TI Pathology of the vessels in cerebral amyloid angiopathy
QU Folia Neuropathologica 1995; 33(4): 207-14
PT journal article; review; review, tutorial
AB We review here current data on congophilic amyloid angiopathy (congophilic angiopathy) or cerebral amyloid angiopathy in both transmissible and non-transmissible cerebral amyloidoses. A beta peptide is the amyloid in congophilic angiopathy of Alzheimer's disease, and in majority of cases of Creutzfeldt-Jakob disease and Gerstmann-Sträussler-Scheinker disease. A variant of Cystatin C is the amyloid in hereditary cerebral hemorrhage with amyloidosis-Icelandic type. The only exception is a curious GSS-like family from Japan characterized by 145 stop codon at the PRNP gene. Both molecular pathology and neuropathology are covered by this review.
ZR 68
MH Amyloid/*chemistry; Amyloid beta-Protein/analysis; Animal; Brain Diseases/etiology/pathology; Cerebral Amyloid Angiopathy/etiology/*pathology; Cerebrovascular Disorders/etiology/pathology; Endothelium, Vascular/*pathology; Human
AD Laboratory of Electron Microscopy and Neuropathology, School of Medicine, Lodz.
SP englisch
PO Polen