NR AHHO
AU Liberski,P.P.
TI "Tubulofilamentous particles" are not scrapie-specific and are unrelated to tubulovesicular structures
QU Acta Neurobiologiae Experimentalis 1995; 55(3): 149-54
PT journal article
AB "Tubulofilamentous particles" has been defined as "thick" tubules, apparently distinguishable from other cytoskeletal elements, in touch-preparations from scrapie- and Creutzfeldt-Jakob disease (CJD)-infected brains. I report here that "tubulofilamentous particles" are nonspecific findings unrelated to "tubulovesicular structures" (TVS) which are the only particles consistently observed in brains of naturally occurring and experimentally induced SSVE.
IN Die in den Gehirnen von Creutzfeldt-Jakob-Kranken gefundenen tubulofilamentösen Partikel sollen auch in normalen Gehirnen vorkommen und daher nicht als typische Symptome anzusehen sein.
ZR 34
MH Animal; Brain/*pathology/ultrastructure; Cattle; Creutzfeldt-Jakob Syndrome/pathology; Encephalopathy, Bovine Spongiform/*pathology; Hamsters; Male; Mesocricetus; Mice; Scrapie/*pathology; Support, Non-U.S. Gov't
AD P.P. Liberski, Medical Academy Lodz, Tumor Biol Labs, Laboratory of Electron Microscopy and Neuropathology, Chair Oncol, 4 Paderewski St, PL-93509 Lodz, Poland
SP englisch
PO Polen