NR AHUE
AU Manuelidis,E.E.; Manuelidis,L.
TI Suggested links between different types of dementias: Creutzfeldt-Jakob disease, Alzheimer disease, and retroviral CNS infections.
QU Alzheimer Disease and Associated Disorders 1989 Spring-Summer; 3(1-2): 100-9
PT journal article; review; review, tutorial
AB Several lines of investigation identify common features of Creutzfeldt-Jakob disease, Alzheimer disease, and retroviral CNS infections. We discuss salient neuropathological, genetic, transmission, and transformation properties that suggest there may be common pathways in the pathogenesis of dementias. We also briefly present potential retroviral mechanisms that may be implicated in all of these dementias.
ZR 76
MH Acquired Immunodeficiency Syndrome/*complications; Alzheimer Disease/genetics/*microbiology/pathology; Animal; Brain Diseases/*etiology/pathology; Creutzfeldt-Jakob Syndrome/genetics/*microbiology/pathology; Human; Retroviridae Infections/*pathology; Support, U.S. Gov't, P.H.S.
AD Yale University School of Medicine, Section of Neuropathology, New Haven, CT 06510.
SP englisch
PO USA
OR Prion-Krankheiten M