NR AHWQ
AU Marsh,R.F.; Hadlow,W.J.
TI Transmissible mink encephalopathy
QU Revue Scientifique et Technique de l'Office International des Epizooties 1992 Jun; 11(2): 539-50
PT journal article; review; review, tutorial
AB Transmissible mink encephalopathy (TME) is a rare disease of ranch-raised mink caused by exposure to an as yet unidentified contaminated food ingredient in the ration. The clinical and pathological similarities between TME and scrapie, together with the indistinguishable physicochemical characteristics of their transmissible agents, suggest that sheep may be the source of infection. However, experimental testing of oral susceptibility of mink to several different sources of sheep scrapie have been unsuccessful. These results indicate that either the feeding of scrapie-infected sheep tissues to mink is not the cause of TME, or that there exists a strain of sheep scrapie having high mink pathogenicity that remains unknown. Additional sources of sheep scrapie need to be tested in mink, and epidemiological investigations of new incidents of TME need to emphasise obtaining a thorough history of past feeding practices.
IN Verschiedene Versuche, Scrapie durch Verfütterung von Schafen auf Nerze zu übertragen, waren nicht erfolgreich.
ZR 33
MH Animal; *Mink; *Prions; Virus Diseases/epidemiology/etiology/pathology/prevention &; control/*veterinary
AD Department of Veterinary Science, Animal Health and Biomedical Sciences, College of Agriculture and Life Sciences, University of Wisconsin-Madison 53706-1581.
SP englisch
PO Frankreich