NR AIIT
AU Mikhailova,G.R.; Cherednichenko,Iu.N.
TI [Karyological characteristics of continuous mouse cell lines infected with the scrapie agent]
OT Kariologicheskaia kharakteristika perevivaemykh linii myshinykh kletok, infitsirovannykh agentom skrepi
QU Tsitologiya i Genetika 1984 Mar-Apr; 18(2): 83-6
PT journal article
AB A karyological study of murine cell line L, latently infected with different strains of the scrapie agent (Compton and C-506) showed that the both variants number of chromosomes and the number of Robertson's translocations of chromosomes decrease insignificantly with an increase in the time of subcultivation. The use of the C-method of differential chromosome staining revealed four new analogous chromosomes in both experimental cell lines. This phenomenon is probably specific for this infected cell model.
MH Animal; Cell Line; Cells, Cultured; Chromosome Banding; English Abstract; Karyotyping; Metaphase; Mice; Mice, Inbred BALB C; Scrapie/*genetics; Sheep; Translocation (Genetics)
SP russisch
PO Sowjetunion