NR AIOP
AU Mori,S.
TI [Kuru]
QU Nippon Rinsho. Japanese Journal of Clinical Medicine 1997 Apr; 55(4): 987-92
PT journal article; review; review literature
AB Kuru, the progressive and fatal neurologic disorder which occurred exclusively among natives of the New Guinea Highlands, were reviewed. Early history of kuru investigation, epidemiology, clinical findings, pathological findings, successful transmission with chimpanzees, from unconventional virus to prion hypothesis and the similarities to "variant of Creutzfeldt-Jakob disease" were discussed in the literature. Although the incidence of kuru has markedly declined with the suppression of cannibalism, it is important from a historical perspective because it was the first human transmissible prion disease to be recognized.
ZR 16
MH Animal; English Abstract; Goats; Human; Kuru/epidemiology/*transmission; Pan troglodytes; Papua New Guinea/epidemiology; Sheep
AD Department of Neurology, Niigata Saiseikai Second General Hospital.
SP japanisch
PO Japan