NR AIVP
AU Neufeld,M.Y.; Josiphov,J.; Korczyn,A.D.
TI Demyelinating peripheral neuropathy in Creutzfeldt-Jakob disease
QU Muscle and Nerve 1992 Nov; 15(11): 1234-9
PT journal article
AB We describe 2 patients of Jewish Libyan descent, who presented with a clinical syndrome compatible with Creutzfeldt-Jakob disease and who were found to have a mutation of codon 200 in the prion protein. The patients developed symptoms and signs of peripheral nerve involvement diagnosed by electrodiagnostic and histopathological studies as demyelinating neuropathy. This may be a rare manifestation of Creutzfeldt-Jakob disease.
MH Action Potentials; Case Report; Codon; Creutzfeldt-Jakob Syndrome/*complications/genetics; Demyelinating Diseases/*complications/diagnosis/genetics; Electrodiagnosis; Electromyography; Human; Male; Middle Age; Muscles/physiopathology; Mutation; Nerve Tissue Proteins/genetics; Neural Conduction; Peripheral Nervous System Diseases/*complications/diagnosis/genetics; PrPsc Proteins; Prions/genetics
AD Department of Neurology, Tel-Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Israel.
SP englisch
PO USA