NR AIXO
AU Nomura,E.; Harada,T.; Kurokawa,K.; Murata,Y.; Ishizaki,F.; Mimori,Y.; Nakamura,S.
TI Creutzfeldt-Jakob disease associated with autonomic nervous system dysfunction in the early stage
QU Internal Medicine 1997 Jul; 36(7): 492-6
PT journal article
AB A 54-year-old man presented with tremor and unusual behavior. He was admitted two months later because of dementia and myoclonus. Periodic synchronous discharges were observed on the electroencephalogram. Based on these findings, we diagnosed the case as Creutzfeldt-Jakob disease. About two weeks after admission, decubitus, bowel dysfunction and hypohidrosis occurred. We observed various autonomic nervous system dysfunctions such as abnormal pupillary response to autonomic drugs, reduced coefficient of variation of R-R interval, and abnormal diurnal blood pressure variation.
IN Bei einem 54 Jahre alten mutmaßlichen Creutzfeldt-Jakob-Patienten traten bereits 2 Monate nach den ersten Verhaltensauffälligkeiten und Tremor, Demens, periodische, synchrone Entladungen im EEG und Myoklonien auf. Schon 2 Wochen nach der Einlieferung traten Druckgeschwüre, Darmfehlfunktionen und verminderte Schweißproduktion auf. Abnorme Pupillenreflexe und Blutdruckschwankungen wiesen auch auf Fehlfunktionen autonomer Nervensysteme hin.
ZR 7
MH Atrophy; Autonomic Nervous System Diseases/*etiology/physiopathology; Brain/pathology/radiography; Case Report; Creutzfeldt-Jakob Syndrome/*complications/diagnosis/pathology; Electroencephalography; Hemodynamics; Human; Magnetic Resonance Imaging; Male; Middle Age; Thalamus/pathology; Tomography, X-Ray Computed
AD Third Department of Internal Medicine, Hiroshima University School of Medicine, Minami-ku.
SP englisch
PO Japan