NR AIYI
AU Nuytten,D.; Wyffels,E.; Michiels,K.; Ferrante,M.; Verbraeken,H.; Daelemans,R.; Baeck,E.; Cras,P.
TI Drug-induced spongiform leucoencephalopathy, a case report with review of the literature
QU Acta Neurologica Belgica 1998 Mar; 98(1): 32-5
PT journal article; review; review of reported cases
AB A nineteen year-old girl developed rhabdomyolysis and central pyrexia after the ingestion of multiple drugs: amphetamines, benzodiazepines, methadone, ethanol, and cocaine. On admission, the patient was deeply comatose and during the hospitalisation asymmetrical spastic quadriparesis was noted. Brain biopsy was diagnostic of spongiform leucoencephalopathy. A review of the literature concerning drug-induced spongiform encephalopathy revealed a large amount of heroin-induced cases. The role of cocaine, however, is less well described. After prolonged hospitalisation, our patient improved clinically and radiologically and could be transferred to a rehabilitation center.
ZR 19
MH Adult; Case Report; Female; Human; Magnetic Resonance Imaging; Prion Diseases/*chemically induced/diagnosis; Substance-Related Disorders/*diagnosis; Tomography, X-Ray Computed
AD Department of Internal Medicine and Neurology, Stuivenberg General Hospital, Antwerp, Belgium.
SP englisch
PO Belgien