NR AJAI

AU Olds,G.R.

TI Kuru and mad cow disease: understanding the prion theory.

QU Cleveland Clinic Journal of Medicine 1998 Jun; 65(6): 291-6

PT journal article

AB A preponderance of evidence indicates that several neurodegenerative disorders are caused by prions: abnormally folded proteins that can induce abnormal folding in other normal protein molecules. Further, these "infections" can cross some species barriers.

MH Encephalopathy, Bovine Spongiform/*physiopathology; Human; Kuru/*physiopathology; *Prions; Protein Conformation; Protein Folding

AD Department of Medicine MetroHealth, Medical Center, Cleveland, USA

SP englisch

PO USA

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