NR AJOP
AU Powers,J.M.; Liu,Y.; Hair,L.S.; Kascsack,R.J.; Lewis,L.D.; Levy,L.A.
TI Concomitant Creutzfeldt-Jakob and Alzheimer diseases
QU Acta Neuropathologica 1991; 83(1): 95-8
PT journal article
AB We report a 69-year-old female with cerebral and cerebellar symptomatology of 15-month duration. At autopsy, both panencephalopathic Creutzfeldt-Jakob and plaque-predominant Alzheimer diseases were found. Plaque amyloid was exclusively of the beta/A4 type, but abundant abnormal protease-resistant protein was identified by Western blot analysis of brain extracts.
MH Aged; Alzheimer Disease/complications/*pathology/radiography; Amyloid beta-Protein/metabolism; Atrophy/pathology; Blotting, Western; Brain/pathology/radiography; Brain Chemistry; Case Report; Creutzfeldt-Jakob Syndrome/complications/*pathology/radiography; Female; Human; Immunoenzyme Techniques; Tomography, X-Ray Computed
AD Department of Pathology, Columbia-Presbyterian Medical Center, New York, NY.
SP englisch
PO Deutschland