NR AKEC
AU Rosenmann,H.; Meiner,Z.; Kahana,E.; Halimi,M.; Lenetsky,E.; Abramsky,O.; Gabizon,R.
TI Detection of 14-3-3 protein in the CSF of genetic Creutzfeldt-Jakob disease
QU Neurology 1997 Aug; 49(2): 593-5
PT journal article
AB The 14-3-3 protein, a protein involved in signal transduction, is present in the CSF of patients with Creutzfeldt-Jakob disease (CJD) and not in patients with other dementing diseases. We show here that this is also true for patients with E200K CJD, but not for healthy carriers of the mutation.
IN Die Autoren fanden das an der Signalübertragung beteiligte Protein 14-3-3 in Creutzfeldt-Jakob-Patienten mit der Glutaminsäure-zu-Lysin-Mutation im Codon 200, jedoch nicht in gesunden Trägern dieser Mutation.
ZR 10
MH Carrier State/cerebrospinal fluid; Creutzfeldt-Jakob Syndrome/*cerebrospinal fluid/genetics; Human; Immunoassay; Mutation; Nervous System Diseases/cerebrospinal fluid/genetics; Proteins/*analysis; Support, Non-U.S. Gov't
AD Department of Neurolog, Hadassah University Hospital, Jerusalem, Israel.
SP englisch
PO USA