NR AKLW
AU Schadel,A.; Löwer,J.; Seifert,E.
TI [Risks of a cartilage-bone bank with reference to HIV infection]
OT Über die Problematik einer Knorpel-Knochenbank angesichts des HIV-Infektionsrisikos
QU HNO 1991 May; 39(5): 177-81
PT journal article; review; review, tutorial
AB Allogenic transplants have an established place in reconstructive procedures. For years it has been suspected that lyophilized dura mater can transmit Creutzfeldt-Jakob disease. HIV infection with fully manifest AIDS and a mortality of up to 100% is now also increasing in significance. It is necessary to assess the risk of transferring HIV with allogenic transplants because HIV passes into the cell via specific surface receptors and is integrated within the chromosome. Experimental data on disinfection and sterilization of allogenic transplants stored within chromosomes and their inactivation are not available. Allogenic transplants are only used in operations for life-threatening disease. As a rule, these are elective operations which must meet the highest safety standards, also with regard to the danger of infection. Collaboration with a transplantation team is essential.
ZR 45
MH Bone Transplantation/*adverse effects; Cartilage/*transplantation; English Abstract; HIV Infections/prevention & control/*transmission; Human; Otorhinolaryngologic Diseases/*surgery; Risk Factors; *Tissue Banks
AD HNO-Klinik, Klinikum Mannheim, Fakultät für klinische Medizin der Universität Heidelberg.
SP deutsch
PO Deutschland