NR AKVQ
AU Shyu,W.C.; Lee,C.C.; Hsu,Y.D.; Lin,J.C.; Lee,J.T.; Lee,W.H.; Tsao,W.L.
TI Panencephalitic Creutzfeldt-Jakob disease. Unusual presentation of magnetic resonance imaging and proton magnetic resonance spectroscopy.
QU Journal of the Neurological Sciences 1996 Jun; 138(1-2): 157-60
KI J Neurol Sci. 1997 Aug;149(2):197; discussion 199-200. PMID: 9171331
PT journal article
AB We present serial magnetic resonance imaging (MRI) scans on a biopsy-verified case of Creutzfeldt-Jakob disease (CJD). The initial MRI scan demonstrated increased T2 signal-intensity within the basal ganglia and thalami. Subsequent MRI scans demonstrated a thin cortex, increased T2 signals diffusely within the white matter including U-fibers, and hypointense T2 signals within the basal ganglia, and thalami. Proton magnetic resonance spectroscopy (1H-MRS) study showed an absence of creatine, choline and N-acetylaspartate signals. By these characteristic findings, serial MRI and MRS studies may be helpful in differentiating CJD from other dementing illnesses.
IN Bei einem Creutzfeldt-Jakob-Patienten wurde zunächst im MRI-Scan eine verstärkte T2-Signalintensität in den Basalganglien und im Thalamus gemessen. Später wurden dann verstärkte T2-Signalintensität diffus in der weißen Substanz einschließlich der U-Fibern und abgeschwächte Signale in den Basalganglien und im Thalamus gemessen. Die Protonenmagnetresonanzspektroskopie (H-1-MRS) ergab das Fehlen von Creatin-, Cholin- und N-Acetylaspartatsignalen.
ZR 10
MH Biopsy; Brain/*pathology; Case Report; Cerebral Cortex/*pathology; Creutzfeldt-Jakob Syndrome/*pathology; Female; Human; *Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy/*methods; Middle Age; Protons
AD Department of Neurology, Tri-Service General Hospital and National Defence Medical Center, Taipei, Taiwan, R.O.C.
SP englisch
PO Niederlande