NR ALHP
AU Sy,M.S.; Gambetti,P.
TI Prion replication - once again blaming the dendritic cell
QU Nature Medicine 1999 Nov; 5(11): 1235-7
PT news
AB The lymphoid system is known to be involved in the propagation and spread of scrapie. However, the identity of the cell type responsible for scrapie replication remains controversial. A new study provides evidence that the follicular dendritic cells in the spleen are the targets of this infectious form of prion (pages 1308-1312).
MH Animal; Dendritic Cells/*immunology; Mice; Prions/*physiology; Scrapie/*immunology/transmission
SP englisch
PO USA