NR ALIS
AU Taguchi,F.; Tamai,Y.; Uchida,K.; Kitajima,R.; Kojima,H.; Kawaguchi,T.; Ohtani,Y.; Miura,S.
TI Proposal for a procedure for complete inactivation of the Creutzfeldt-Jakob disease agent
QU Archives of Virology 1991; 119(3-4): 297-301
ER Arch Virol 1992;122(3-4):411
PT journal article
AB We have examined complete inactivation conditions on brain homogenates from mice affected with Creutzfeldt-Jakob disease agent, and recommend for routine use a reliable procedure first treating the affected materials with 1 N NaOH for 60 min and then autoclaving at 121 degrees C for 30 min.
MH Animal; Brain/*microbiology; Creutzfeldt-Jakob Syndrome/*microbiology/transmission; Heat; Human; Mice; Mice, Inbred BALB C; Sodium Hydroxide; Sterilization/*methods; Support, Non-U.S. Gov't; Time Factors
AD Department of Microbiology, School of Hygienic Sciences, Kitasato University, Kanagawa, Japan.
SP englisch
PO Österreich